General toxicology
We have an experienced professional research team in toxicology and an experienced team of top experts at home and abroad, who can provide customers with scientific test design and dose selection to ensure the smooth conduct of toxicology tests. Our general toxicology trials comply with the international GLP regulatory code and are designed to meet the requirements of the NMPA (CFDA), US FDA, OECD and ICH guidelines to meet the requirements of clinical trials or marketing applications in different countries and regions.
Category: Non-clinical safety evaluation
Medicines for human purposes
We have an experienced professional research team in toxicology and an experienced team of top experts at home and abroad, who can provide customers with scientific test design and dose selection to ensure the smooth conduct of toxicology tests. Our general toxicology trials comply with the international GLP regulatory code and are designed to meet the requirements of the NMPA (CFDA), US FDA, OECD and ICH guidelines to meet the requirements of clinical trials or marketing applications in different countries and regions.
Type of test
? Dose range determination test
? Single dose toxicity test
? Repeated administration toxicity test with toxicity (1/3/6/9 months)
? Allergic test:
- Active whole body allergy test, passive skin allergy test, active skin allergy test and photoallergy test
- Maximization test in guinea pigs, closure patch test and local lymph node test in mice
? Hemolytic test: in vitro hemolytic test and animal hemolytic test
? Local irritation test: blood vessel, skin, mucous membrane, muscle stimulation test
? In vivo phototoxicity test
? In vitro phototoxicity test (3T3 cells)
? T cell dependent antibody response test
Test animal species
Mice, rats, guinea pigs, rabbits, dogs, non-human primates (crab-eating monkeys, rhesus monkeys) miniature pigs, golden hamsters, immunodeficient mice
Route of administration
Oral (gavage, capsule) and nasal feeding, skin and mucous membranes, intravenous (rapid infusion, continuous infusion)
Subcutaneous, intradermal and intramuscular injections
Eye, joint cavity, vagina, rectum, intracranial, intratumoral injection
